Advances in Neuromodulation for Functional Recovery after Spinal Cord Injury
3:00 PM - 4:00 PM UTC
Moderated by Rushna Ali, M.D.
Clinical Instructor, Michigan State University
Director of Restorative and Functional Neurosurgery
Spectrum Health Medical Group
Grand Rapids, MI
Prof Enrico Rejc
Assistant Professor, Department of Neurological Surgery, University of Louisville, USA.
> Topic: Spinal Cord Epidural Stimulation for Lower Limb Motor Function Recovery in Individuals with Motor Complete Spinal Cord Injury
Severe spinal cord injury (SCI) dramatically impairs sensorimotor function, resulting in paralysis and a drastic decrease in quality of life. However, the scientific evidence presently available challenges the belief that individuals with chronic and severe SCI have essentially no expectation for neurological and functional recovery. This talk will summarize a decade of findings related to the application of spinal cord epidural stimulation below the level of injury in individuals with complete SCI, which have led to unprecedented proof of principle that recovery of motor function, even at a chronic stage, is potentially available.
Prof Parag Gad
Assistant Project Scientist, Department of Neurobiology, University of California, Los Angeles.
> Topic: Transcutaneous Electrical Spinal Cord Neuromodulator (TESCoN) for Recovery of Neurogenic Bladder Dysfunction after Severe Paralysis
It is commonly assumed that restoration of locomotion is the ultimate goal after spinal cord injury (SCI). However, lower urinary tract (LUT) dysfunction is universal among SCI patients and significantly impacts their health and quality of life. TESCoN leads to improvement and normalization of the LUT function after SCI. TESCoN offers several advantages over current therapies for LUT dysfunction due to SCI. It is non-invasive. If the intervention is not tolerated by the subject, it can be immediately discontinued. Further, we demonstrate that TESCoN can modulate the activity of the spinal cord to elicit a specific response in the LUT. Finally, TESCoN can be easily integrated with other rehab programs that a patient may be undergoing.